Pharma Nord were the first company to introduce coenzyme Q10 (Q10) supplements to the European market, Bio-Quinone Q10 is recognised as a market leader in terms of documented quality and bioavailability. It was also the subject of a recent study which showed that Pharma Nord’s Bio-Quinone Q10 when taken by patients with chronic heart failure significantly reduced mortality risk and improved symptoms.
New treatment improves survival among those with weak hearts
Is it possible to protect heart patients against premature death by boosting the energy production of the heart muscle? The results of a recently published international study lend support to this new strategy.
With rather intriguing results showing an improvement of heart failure symptoms and nearly half as many deaths, the study may have paved the road for an improved treatment of chronic heart failure in the future.
The Danish cardiologist and researcher, Chief Physician Svend Aage Mortensen from The Heart Center of Copenhagen University Hospital, headed the international trial, Q-Symbio, and describes the study as both exciting and promising. The Q-Symbio study was published recently in the esteemed Journal of the American College of Cardiology.
Strength to the heart
“The recommended medical treatment for heart failure is primarily based on inhibiting various hormonal factors that are activated with this disease and which strain the heart. For instance, the increased adrenalin levels are blocked. The new therapy, in contrast, is aimed at supporting biological processes that relate to cellular energy metabolism,” Dr. Mortensen explains.
The compound that was tested on a large group of patients with chronic heart failure is coenzyme Q10 (Pharma Nord’s Bio-Quinone Q10), a naturally occurring coenzyme which all cells need in order to produce energy. The cells of the heart muscle are particularly dependent on this compound in order to function optimally, and studies have found that coenzyme Q10 levels are lower in tissue from chronically failing hearts.
Breaking the vicious circle
“Supplementing with coenzyme Q10, which is a completely natural compound, compensates for this deficiency. Theoretically, it helps to break the vicious circle that occurs in chronic heart failure,” Dr. Mortensen explains.
The results of the study clearly indicate that the treatment works. Those patients who were given coenzyme Q10 had substantially lower mortality risk. In addition, there were fewer hospitalizations among the Q10 treated, and their symptoms were significantly improved.
Nearly half as many deaths
A total of 420 patients with chronic heart failure participated in the Q-Symbio study, with each patient undergoing a total of two years of treatment. Half of the patients were assigned to three daily 100 mg capsules of coenzyme Q10 (Pharma Nord’s Bio-Quinone Q10), while the other half got the same amount of identical dummy capsules with an inactive placebo. The patients in both groups continued with their rather extensive regimen of medicine that is prescribed for heart failure.
After two years, there were 43% fewer heart-related deaths in the Q10 group compared with the placebo group. In addition, there were 43% fewer heart-related complications among the Q10-treated participants, including among other things hospitalization due to worsening of the heart failure.
Doctor Mortensen suggests that coenzyme Q10 may play an important role as an adjuvant to conventional heart failure therapy. No side effects were observed with the substance, and an effect was observed in the patients, even though they had already been given the recommended heart failure treatment.
The heart’s natural source of energy
All cells in the body use coenzyme Q10 in order to make energy that is needed for normal cellular functioning. The body synthesizes the substance but the endogenous production of coenzyme Q10 tapers off with increasing age and may also be compromised by disease. The cells of the cardiac muscle are particularly energy-dependent, which is why these cells contain larger concentrations of coenzyme Q10 than cells in other tissues. In heart failure, however, the situation is different. Coenzyme Q10 levels in the heart drop, causing an energy shortage that prevents the heart muscle from contracting with its usual force. This is what causes shortness of breath and chest pain. When people with heart failure take supplements of coenzyme Q10 the energy turnover in their heart muscle cells is stimulated and that is how the heart gets back its strength. Bio-Quinone Q10 is the official reference product (gold standard) of international coenzyme Q10 research. It has been selected by the International Coenzyme Q10 Association.
Support your body’s energy production
Coenzyme Q10 is a vitamin-like substance required by every cell in our bodies to produce energy. Most is manufactured within our bodies but our ability to do this decreases with age. In fact, our natural Q10 levels can decline from as early as our mid-twenties. Q10 is also depleted by chronic illness and intense physical exercise. Pharma Nord’s Bio-Quinone Active Q10 was the first Q10 formula to be introduced to Europe more than 25 years ago and is used to combat fatigue and tiredness, as well as to improve heart health.When it comes to Q10 supplements, the way the Q10 is formulated really does count. Pharma Nord dissolves the Q10 in oil and uses a special process to ensure the Q10 crystals can be easily absorbed by our bodies.
For more information, please visit www.q10.co.uk